The Sartorius Life Sciences Group has released its second edition of the “High-Throughput Screening (HTS) by Cytometry” textbook, designed to support new and experienced researchers who use flow cytometry and want to learn more about the special capabilities of HTS cytometry.

Those using conventional systems will discover how the speed, efficiency and ease of use provided by the iQue^® HTS by Cytometry Platform can facilitate regular workflows. Laboratories already know iQue^® The platform can use this manual to obtain information about new reagents, test kits and software releases.

This routine publication contains up-to-date Sartorius publications, allowing researchers to stay informed about the newest use cases of cytometric HTS in well-known and developing areas.

Research laboratories today face immense pressure to design larger and more complex screening approaches, often with limited samples, resources and expertise. Using more complex cellular models, such as stem cells or patient-specific materials, adds another layer of complexity, requiring more sophisticated analysis to obtain meaningful data, and in less time.

Jonah Riddell, PhD, Sartorius Product Manager for iQue^® Platform

“Workflows that deliver these capabilities and enable scientists to make better decisions are essential to being first to publish or commercialize.” As leading experts in HTS cytometry, we created this manual to demonstrate how this powerful technology meets the unique requirements of high-throughput screening campaigns.

Flow cytometry technology is continually evolving to meet the demands of laboratories designing breakthrough medicines. The iQue^® The HTS cytometry platform was specially developed to meet this growing need for speed and efficiency.

This publication allows readers to easily navigate topics of interest, using resources such as detailed workflow descriptions, in-depth application examples, and direct links to external resources for additional learning.

The chapters highlight iQue^® HTS use cases in the areas of cellular health, secreted proteins, cell line development, biologics discovery, immune cell models, and cell-based therapies, including areas on novel drug modalities. antibodies and advanced cellular models, such as stem cells and organoids.

This manual covers the integrated iQue Forecyt in more detail^® software, which replaces the multiple data analysis packages usually required in other protocols. This informative publication also describes its instant data visualization, smart portal, plate-level analyzes and other sophisticated instrumentation.

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Sartorius is a leading international supplier of pharmaceutical and laboratory equipment. Through our innovative products and services, we help our customers around the world to reliably and cost-effectively implement their complex and quality-critical biomanufacturing and laboratory processes.

The Group’s companies are brought together under the roof of Sartorius AG, listed on the Frankfurt Stock Exchange and holding the majority stake in Sartorius Stedim Biotech SA Listed on the Paris Stock Exchange, this subgroup is mainly composed of the Bioprocess Solutions Division.

Innovative technologies enable medical progress

An increasing number of medicines are biopharmaceuticals. These are produced from living cells using complex, time-consuming and expensive procedures. The Bioprocess Solutions division provides the essential products and technologies to achieve this.

In fact, Sartorius pioneered and set the standards for single-use products that are currently used in all biopharmaceutical manufacturing processes.

Making life in the laboratory easier

Laboratory work is complex and demanding: despite repetitive analytical routines, laboratory staff must perform each step in a very focused and careful manner to obtain accurate results.

The Laboratory Products and Services division helps laboratory personnel excel as its products, such as laboratory balances, pipettes and laboratory consumables, minimize human errors, simplify workflows and reduce physical workloads .

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